Table 1

Table 1. Breast Cancer Drugs in the Market

 

Product

Class

Target

Clinical Stage

Manufacturer

Arimidex

 

 

Market

AstraZeneca

Aromasin

 

 

Market

Pfizer

Avastin

 

 

 

Genentech

Femara

Hormone

Aromatase inhibitor

Market

Novartis

Herceptin

 

 

 

Genentech

Ixabepilone

 

 

 

BristolMyersSquibb

Taxotere

Tubulin inhibitor

Microtubulin

Market

Sanofi-Aventis

Taxol

 

 

Market

Bristol-Myers Squibb

Tykerb

 

 

 

GlaxoSmithKline

Xeloda

 

 

 

Roche

 

Table 2. Breast Cancer Drugs in the Clinical Trials

 

Product

Class

Target

Clinical Stage

Manufacturer

ABT-510

Antiangiogenic

Pro-angiogenic growth factors

Phase I

Abbott

Arimidex

 

 

Market

AstraZeneca

Aromasin

 

 

Market

Pfizer

Dendritic/

cancer cell fusion

Vaccine

Immune system

Phase II

Genezyme

Femara

Hormone

Aromatase inhibitor

Market

Novartis

ISIS2503

Antisense

Ha-ras

Phase II

Isis

MDX-010

Antibody

CTLA-4

Phase II

Medarex

Panzem

Antiangiogenic

Microtubule

Phase II

EntreMed

Perifosine

Kinase inhibitor

AKT/protein kinase B

Phase II

Aeterna Zentaris

Genasense

Small molecule

Bcl-2

Phase II

Aventis and Genta

Taxotere

Tubulin inhibitor

Microtubulin

Market

Aventis

Taxol

 

 

Market

Bristol-Myers Squibb

Theratope

Vaccine

Sialyl Tn

Phase III

Biomira

Tykerb

 

 

 

GlaxoSmithKline