Product

Class

Target

Clinical Stage

Manufacturer

ABX-EGF

Antibody

Epidermal growth factor receptor

Phase II

Amgen and Abgenix

ALVAC-CEA-B7.1

Vaccine

Immune system

Phase II

Aventis

Avastin

Antibody

VEGF

Market

Genentech

Avicine

Vaccine

hCG

Phase II

AVI Biopharma

Campto

(Irinotecan)

Topoisomerase

Topoisomerase I

Market

Aventis and Merck

Camptosar

Eloxatin

CEAcide

Antibody

Carcinoembryonic antigen

Phase II

Immunomedics

EP-2101

T cells

T cells

Phase II

Epimmune

Erbitux (Cetuximab)

Antibody

EGFR

Market

Bristol-Myers Squibb and ImClone

IMC-1C11

Antibody

VEGF

Phase I

ImClone

Genasense

(Oblimersen sodium)

Small molecule

Bcl-2

Phase II

Aventis and Genta

Panitumumab

Amgen

PTK787

Kinase inhibitor

VEGFR tyrosine kinase inhibitor

Phase II

Novartis

Rubitecan

Topoisomerase

Topoisomerase I

Phase II

SuperGen

Taxotere

Tubulin inhibitor

Microtubulin

Phase II

Aventis

Tezacitabine

Nucleoside analogue

DNA

Phase II

Chiron

Xeloda

XR303

Antibody

Carcino-embryonic antigen

Phase I

Xenova