Product

Class

Target

Clinical Stage

Manufacturer

Campath

Progressive B-cell chronic lymphocytic leukemia

Genzyme

Depocyt

Nucleoside analogue

DNA

Market (Lymphomatous meningitis, acute lymphomatous leukemia)

Enzon

Genasense

(Oblimersen sodium)

Antisense

Bcl-2

Phase III

(Chronic lymphocytic leukemia)

Aventis and Genta

Gleevec

Kinase inhibitor

Tyrosine kinase inhibitor

Market

(chronic myelonic leukemia)

Novartis

HuMy9-6-DM1

Antibody

CD33

Phase I

(Acute myeloid leukemia)

ImmunoGen

MG98

Antisense

DNA methyltransferase

Phase I

(Acute myeloid leukemia and myelodysplasia)

MGI Pharma

Novantrone

Topoisomerase

Topoisomerase II

Market

OSI

PEG-Intron

Immunomodulatory

Immune system

Phase III

(Chronic myelogenous leukemia)

Enzon

PKC412

Kinase inhibitor

Protein Kinase C

Phase I

(Acute myelonic leukemia)

Novartis

Revimid

Immunodomulatory

Multiple

Phase II

(Chronic myelonic leukemia and myelodysplastic)

Celgene

GVAX

Chronic myelogenous leukemia

Cell Genesys