Product

Class

Target

Clinical Status

Manufacturer

ABX-MA1

Antibody

MUC18

Phase I

Abgenix

Bay 43-9006

Small molecule

RAF kinase

Phase II

Bayer and Onyx

Canvaxin

Vaccine

Immune system

Phase III

CancerVax

Dendritic/

cancer cell fusion

Vaccine

Immune system

Phase II

Genezyme

Genasense

(Oblimersen sodium)

Antisense

Bcl-2

Phase III

Aventis and Genta

GMK

Vaccine

GM2 ganglioside

Phase III

Perogenics

MDX-010

Antibody

CTLA-4

Phase  II

Medarex

Vitaxin

Antibody

Integrins

Phase II

MedImmune

Melan-A/Mart-1 and gp100 melanoma

Gene therapy

Immune system

Phase II

Genzyme

Melaniccine

Vaccine

Immune system

Market

Corixa

PEG-Intron

Immunomodulatory

Immune system

Phase III

Enzon

Proleukin

Immunomodulatory

Immune system

Market

Chiron

Taxotere

Tubulin inhibitor

Microtubulin

Phase III

Aventis