Chiron Corp

4560 Horton Street
Emeryville, CA 94608

USA

Phone: (510) 655-8730
Fax: (510) 655-9910
Web Site: http://www.chiron.com/

A. Company Profile

Chiron (NASDAQ:CHIR) is one of the world's leading biotech companies. The company's product portfolio includes innovative treatments across a wide range of therapeutic areas. There are extensive discovery and development programs in the field of oncology at Chiron.

B. Products

Product Pipelines

1. Angiozyme

Angiozyme is a synthetic ribozyme that specifically inhibits vascular endothelial growth factor, a key component in the angiogenesis pathway. Since angiogenesis plays a significant role in the growth and metastasis of several important human tumors such as lung cancer, breast cancer, melanoma and renal cell carcinoma, Angiozyme has the potential to benefit a large group of patients.

2. Chir258

Chir258 is a small molecule anti-cancer compound.

3. Proleukin

Proleukin (aldesleukin, interleukin-2) has a demonstrated record in the treatment of metastatic melanoma and metastatic renal cell cancer and is being tested in combination therapy with monoclonal antibodies for the treatment of non-Hodgkin's lymphoma.

4. Tezacitabine

Tezacitabine (FMdC) interrupts DNA replication and is a nucleoside analogue, to treat cancer. Nucleoside analogues are a class of drugs that affect DNA synthesis.